Research of the APCE covers a wide spectrum of protein-related projects. This includes:

  • Synthesis and characterization of nanoparticles for drug delivery systems
  • Design and production of three dimensional micro-structured biomaterials
  • Mathematical modelling
  • Computational protein design
  • Molecular dynamic simulations of proteins and biological membranes and the interactions they participate in
  • Computational modulation of protein-protein interactions
  • Molecular and biochemical characterization of membrane proteins
  • Functional analysis of G protein-coupled receptors
  • Cellular and cell-free pathway engineering
  • Synthetic signaling pathways
  • Design and synthesis of peptides
  • Production of recombinant proteins for medical and industrial applications
  • Targeted and untargeted proteome analyses
  • Programmable protein linkages
  • In vitro evolution of proteins

Within the research projects members of the APCE try to either decipher biological principles, understand biological building blocks, reconstruct or redesign biological building blocks or apply biological principles in metabolic engineering, design of bio-hybrid polymers and construction of novel cellular or cell-free systems for medical applications. All research projects are carried out by individual research teams. The APCE supports scientific progress by providing a communication platform fostering efficient exchange between the different disciplines and by providing access to state-of-the-art research facilities. These facilities include mass-spectrometry, X-ray protein structure analysis, peptide synthesis, bioinformatics and other protein-related technologies.